Nutritional supplement

 

 

 

One capsule contains:

• Magnesium orotate    - 700 mg.
  

Recommendations for use:

 

Magnesium orotas

Magnesium orotas is the compound of magnesium and orotic acid. Orotic acid was first extracted from the whey of cow milk. Small amounts or orotic acid can be found in vegetables, wheat, beef and yogurt. It was called vitamin B13 and belonged o the group of vitamin B. This vitamin is produced in the intestinal tract by beneficial bacteria and it participates in the metabolism of Folic acid and vitamin B12. It improves the absorption of magnesium and calcium and participates in the synthesis of RNA and DNA. The compound of magnesium and orotic acid is called magnesium orotas and can penetrate the cell easily by connecting proteins and dissolving in fats easier. Magnesium orotas is absorbed easier than other magnesium salts. Magnesium orotas increase the physical endurance, supplements the deficiency of magnesium in case of hypertension, diabetes, dementia, osteoporosis. It can be administrated for migraine, asthma, COPD, cardiac pains, arrhythmias, and atherosclerosis.

The importance of magnesium orotas to one’s heart

1.Magnesium orotas can improve the energetic processes of myocardium.
2.Orotic acid, affected by the enzyme orotas phosphorylribosyltransferase, converts into uridine that takes part in the synthesis of pyrimidines. That is why the amount of myocardial purine and pyrimidine increases.
3. Orotic acid increases the damaged cardiac muscles tolerance to ischemia.
4.Magnesium orotas can decrease the impairment of the function of cardiac muscle and structural changes in cardiomiopathy.
5.Magnesium orotas can improve the toleration of physical strain for the people with coronary artery disease.
6.Magnesium orotas has inotropic (the force with which the heart muscle contracts) qualities.
7.Magnesium orotas suppress the development of atherosclerosis: orotic acid connects the ribose of blood vessels. During this process, magnesium ion loosens form magnesium orotas. This ion locally activates the enzymes that take part in cholesterol metabolism.  

Scientific researches demonstrating the efficiency

* In a randomized auditorial trial 32 patients that underwent coronary bypass surgery were administered magnesium orotas and placebo. After 8 weeks the functional heart parameters improved and the risk of extrasystolia decreased 63% for those who were administered magnesium orotas. In placebo group there was no such effect. ( BRANEA I. ; GAITA D. ; DRAGULESCU St. I. ; SOCOTEANU I. ; LUCA C. ; MANCAS Silvia ; DRAGAN Simona ; IURCIUC M. ; VELIMIROVICI Dana ; GASPAR M. ; FLUTURE A. ; IONAC Adina ; DEUTSCH P. ; PESCARIU S. ; PETRESCU L. ; BRANEA H. ; MUT B. ; DINA C. ; CRASNIC M. ; SARU C. A. ;  Assessment of treatment with orotate magnesium in early postoperative period of patients with cardiac insufficiency and coronary artery by-pass grafts (ATOMIC). Revue roumaine de médecine interne  (Rev. roum. méd. interne)  ISSN 1220-4749,  1999, vol. 37, no3, pp. 287-296 [10 page(s) (article). )
* 84 patients with the diagnosis of mitral valve prolapse were administered standard treatment and an additional magnesium orotas therapy. After 6 months of additional magnesium orotas administration, the symptoms of mitral valve prolapse disappeared or were significantly reduced and the functional heart values increased for more than 50% of the patients.
* 14 patients with coronary artery disease and the dysfunction of left ventricle were administered magnesium orotas or placebo for 4 weeks. An improved left ventricle’s systolic and diastolic function was determined in the group, treated with magnesium orotas.
* Many clinical trials determined the efficiency of magnesium orotas in angina pectoris, increased blood pressure, rapid pulse and in improving the elasticity of blood vessels.

Dosage

Take 2 capsules 2 times a day. After 1−2 weeks take 1 capsule 2 times a day.

Literature: