Nutritional supplement

Composition

One tablet contains:

• Milk Thistle Silybum marianum) extract           -  83,33 mg,
• Turmeric (Curcuma longa) extract                    -   50 mg,
• Turmeric (Curcuma longa) powder                -  58,33 mg,
• Artishoke (Cynara scolymum) powder          -  108,33 mg,
• Blessed Thistle (Cnicus benedictus) powder -  108,33 mg,
• Oregon Grape (Mahonia aquifolium) powder  - 108,33 mg,
• Lecithin                                                       -  150 mg,
• Cholic bitartrate                                            -  100 mg,
• Inositol                                                         - 100 mg,
• DL-Methionine                                                -  50 mg,
• Vitamin B6                                                    - 2,56 mg,
• Noni friut (Morinda citrifolia) powder               -  66,66 mg,
• Liver powder                                                  - 100 mg.
  
  

Recommendations for use:

• digestion disorder,
• overeating.

Action of active substances

Blessed Milk Thistle

Scientific research shows that Blessed Milk Thistle active substances especially silymarin protect liver from viruses, toxins, alcohol and hepatotoxic medicines because they bind to the hepatic cells membrane outer receptors, inhibit the activity of circulating hepatotoxic substances and increase the level of the main liver antioxidant glutathione in liver, stomach and intestine. Antioxidative effect of silymarin is 10 times more potent that vitamin E. It also stimulates DNR, protein synthesis and the regeneration of the damaged hepatocytes. Silymarin decreases hepatic enzymes and bilirubin concentration in blood, stimulates regeneration of the hepatocytes, inhibits the formation of the cholesterol stones. Because of such effect silymarin Blessed Milk Thistle is suitable for treatment of various liver diseases: toxic liver disease caused by alcohol and side effects of the drugs, hepatic cirrhosis, gall bladder lithiasis.

Turmeric extract

Stimulates the production and secretion of the bile, regulates gastrointestinal tract function.

Artichoke extract

Stimulates the production and secretion of the bile.

Blessed Thistle powder

Improves digestion.

Oregon-grape root powder

Diminishes the inflammation and improves digestion.

Methionine

It is an amino acid that stimulates hepatic cells regeneration and detoxicative function of the liver.

Lecithin, choline and inositol

Activates lipids and cholesterol metabolism in the liver

Vitamin B6

Important for detoxicative liver function.

Great morinda fruit powder

Strengthen the immunity

Scientific researches demonstrating the efficiency

* 36 patients with alcohol induced liver disease were followed for 6 months. First group received silymarin, second – placebo. The administration of silymarin normalized bilirubin, asparagines and alanine aminotransferases levels, improved liver hystologic indicators. Conclusion: silymarin has hepatoprotective property, improves liver function. (Feher J, Deak G, Muzes G, et al. Liver-protective action of silymarin therapy in chronic alcoholic liver diseases. Orv Hetil (HUNGARY) 130:2723-2727; 1989).
* Randomized double blind placebo controlled study was performed with 105 hepatocirrhotic patients. They received silymarin for almost two years. It was noticed that mortality due to the hepatic insufficiency decreased significantly in silymarin group compared to placebo. (Clinical Study 1989).
* In Finland 1981 double blind study was performed with 106 patients with alcoholic liver disease. They received silymarin. The blood test and biopsy results showed that silymarin effectively improved hepatic function.
* Double blind placebo controlled study with silymarin was performed in 2000-2002. It was proved that administration of silymarin decreases mortality due to the hepatic cirrhosis and chronic hepatitis rates, stops the progression of the liver diseases, improves life quality, it becomes easier to diagnose liver infections.

Dosage

1-2 tablets 3 times after meals.

Literature:

1. Agency for Healthcare Research and Quality. Milk thistle: effects on liver disease and cirrhosis and clinical adverse effects. Summary, evidence report/technology assessment: number 21, September 2000.
2. Bhatia N, Zhao J, Wolf DM, Agarwal R. Inhibition of human carcinoma cell growth and DNA synthesis by silibinin, an active constituent of milk thistle: comparison with silymarin. Cancer Lett. 1999;147(1-2):77-84.
3. Feher J, Deak G, Muzes G, Lang I, Neiderland V, Nekan K, et al. Hepatoprotective activity of silymarin therapy in patients with chronic alcoholic liver disease. Orv Hetil. 1990;130:51.
4. Ferenci P, Dragosics B, Dittrich H, Frank H., Benda L, Lochs H, et al. Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. J Hepatol. 1989;9:105-113.
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6. Simon Mills & Kerry Bone. Principles and Practice of Phytotherapy. Modern Herbal Medicine. 2000.
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8. Melvyn R. Werbach & Michael T. Murray. Botanical Influences on Illness. A source book of clinical research. 1994
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10. Racz K, Feher J, Csomos G, Varga I, Kiss R, Glaz E. An antioxidant drug, silibinin, modulates steroid secretion in human pathological adrenocortical cells. J Endocrinol. 1990 Feb;124(2):341-5
11. Svendsen BS, Gjellestad A, Eivindson G, Berentsen G, Jacobsen D. Serious mushroom poisoning by Cortinarius and Amanita virosaTidsskr Nor Laegeforen. 2002 Mar 20;122(8):777-80.
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