Nutritional supplement

Composition

One capsule contains:

• Chitosan powder                               380 mg,
• Pineapple (Ananas comosus) powder   100 mg,
• Vitamin C                                          25 mg.

Recommendations for use:

• for those who want to decrease the absorption of fats in organism and to loose overweight,
• can be used in treatment of cardiovascular diseases.

Action of active substances

Chitosan

Chitosan is a fibrous food substance that is excreted from the organism without being digested. So it has no additional calories and is recommended for the people who want to lose some weight. Fatty food provides our organism with fats that accumulate in various organs. Fats that are absorbed by chitosan do not get into blood circulation system. Chitosan absorbs two thirds of fats that the organism receives from food, forms the compound and is excreted from the organism. Besides, chitosan helps to control the blood pressure, effectively reduce the blood cholesterol level by inhibiting low density lipoprotein. It has no effect on high density lipoprotein metabolism and it has a positive effect on cardiovascular system. Chitosan can not eliminate the fats that are in the tissues of the body. To receive a better effect it is important to avoid extremely fat food and to keep exercising.
Chitosan decrease the absorption of fats in the organism and gives the feeling of satiety.

Pineaple powder

Pineaple powder contains of enzyme bromelain and food fibers. These substances improve digestion and prevent from constipation.

Vitamin C

Vitamin C activates chitosan and increases it's ability to absorb fats and cholesterol.

Effectiveness proving scientific research

* Scientific literature describes the results of 14 trials with 1131 people. Conclusions: chitosan reduced the weight about 2 kg (P < 0.00001), the level of total cholesterol - 0.2 mmol/l (P < 0.00001), systolic blood pressure - 6 mmHg (P < 0.0001), diastolic – 4 mmHg (P < 0.00001) and caused no side effects. ( Ni Mhurchu C, Dunshea-Mooij CAE, Bennett D, Rodgers A).
* In double blind trials in Poland people with obesity were divided into two groups. One group received 1.5 g chitosan, another group - placebo. Chitosan group reached significant weight loss, placebo group did not reach such results. Zahorska-Markiewicz B, Krotkiewski M, Olszanecka-Glinianowicz M, Zurakowski A. Effect of chitosan in complex management of obesity. Pol Merkuriusz Lek 2002;13:129–32).
* 30 obese people were administered chitosan and placebo for 2 weeks in randomized, double blind, placebo controlled trial in Finland, 1994. The conclusions stated that chitosan effectively reduces overweight.
* After 1 month of administration of chitosan the weight of obese people reduced, arterial pressure became normal and body weight index decreased from 31 to 29.

Dosage

1 to 2 capsule daily before meals.

Literature:

1. Mason P. Dietary supplements, Chitosan 46-47.
2. Han LK, Kimura Y, Okuda H. Reduction in fat storage during chitin-chitosan treatment in mice fed a high-fat diet. Int J Obes Relat Metab Disord 19994;23:174-179.
3. Pittler MH, Abbot NC, Harkness EF. Randomized, double –blind trial of chitosan for body weight reduction. Eur J Clin Nutr 1999; 53;379-381.
4. Woulijoki E, Hirvela T, Ylitalo P. Decrease in serum LDL cholesterol with microcrystalline chitosan. Methods Find Exp Clin Pharmacol 1999; 21:357-361.
5. Chitosan and fat absorption. November 2000.
6. Zahorska-Markiewicz B, Krotkiewski M, Olszanecka-Glinianowicz M, Zurakowski A. Effect of chitosan in complex management of obesity. Pol Merkuriusz Lek 2002;13:129–32
7. Ho SC, Tai ES, Eng PH, et al. In the absence of dietary surveillance, chitosan does not reduce plasma lipids or obesity in hypercholesterolaemic obese Asian subjects. Singapore Med J 2001;42:006–10.
8. Pittler MH, Abbot NC, Harkness EF, Ernst E. Randomized, double-blind trial of chitosan for body weight reduction. Eur J Clin Nutr 1999;53:379–81.
9. Muzzarelli RA. Clinical and biochemical evaluation of chitosan for hypercholesterolemia and overweight control. EXS 1999;87:293–304
10. Koide SS. Chitin-chitosan: properties, benefits and risks. Nutr Res 1998;18:1091–101