| Cal-Mag-Zinc plus |
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![]() Composition One capsule contains:
Recommendations for use
Action of active substances Calcium Calcium is one of the most important minerals of human organism that is necessary for strengthening of bones. The largest amount of calcium can be found in bones and teeth; it ensures their strength. Small amounts of calcium that circulate in the blood help in formation of the materials, which regulate digestion, energy circulation, and metabolism. Calcium helps food materials to accesses the cell, important for the maintenance of cell membranes conduction, circulation of nerve impulse to the muscles and blood coagulation. More than 90 percent of calcium of human organism is concentrated in a bone tissue in a form of carbonates and phosphates. The organism takes calcium from bones for the accomplishment of all mentioned functions. In case people use products that contain small amounts of calcium, the bones become more fragile and week, develops osteoporosis, available bone breaks. Vitamin D is necessary for resorption of calcium from intestine. Magnesium In various compounds of magnesium there is an unequal amount of elemental magnesium. The largest amount of pure magnesium is found in magnesium oxide. In magnesium oxide there are 5,9-12 times more of elemental (pure) magnesium than in organic magnesium salts (lactate, gluconate, and aspartate). Magnesium oxide reduces enlarged gastric acidity, melts properly in gastric juices and composes a form of magnesium that is easy to adopt – magnesium chloride, which is very easily adopted in the thin intestine and does not interfere with intestine microflora. Magnesium is one of the most important minerals. Magnesium participates in the activity of nervous system, in the processes of thermoregulation, regulates systoles‘ rate and force, and relaxes muscles, necessary for concentration of energy in the cells, important for calcium circulation. Magnesium also widens vessels, regulates blood pressure, improves peripheral blood circulation. Zinc Zinc is an element that can be found in the composition of 3000 proteins of human organism; it participates in more than 200 of ferment reactions. Zinc can be found in oysters, beef, turkey meat, beans, nuts, grains, pumpkin seeds and sunflowers. In the human organism zinc is distinguished only by few types of cells: cells of forward brain part, cells of spit glands, cells of prostate and cells of intestine. The lack of zinc develops when there is a too small amount of zinc in the received food or its absorption is disturbed. The lack of zinc also can be felt because of eating an inferior food or being on strict vegetarian diets. Lack features: hair slip, skin cracks, nail „blowing“, damaged organism tissues, slow healing of wounds, slackened sexual development, maturation, growth, weakened immune system, emerged skin rashes, diarrhoea. According to the data of clinical researches there was determined a fact that together with other antioxidants zinc is able to block retina degeneration; also it is useful while decreasing prostate hyperplasia. Zinc is important for sight, taste, sense, smell functions and memory. These functions fluster because of the lack of zinc. Zinc salts help to fight effectively with viruses and bacteria. Infections of digestive tract sharply decline in case of using zinc. There is an idea that this happens because of antimicrobial effect of zinc or because of the absorption of zinc and repeated release of zinc from immune cells (granulocytes release zinc) or because of both mentioned reasons. Vitamin B6 Vitamin B6 enters nerve cells and helps to assimilate magnesium better. Vitamin B6 regulates cells proliferation and differentiation, protein metabolism. This vitamin influences fermentation processes in the brain, stimulates hemoglobin production, lipid and carbohydrate metabolism. Vitamin D Vitamin D (calcipherol) is a fat soluble vitamin. The most important forms of it include Vitamin D2 (ergocalcipherol) and Vitamin D3 (cholecalcipherol). The sources of Vitamin D are fish oil, fatty fish, and yolk. One of the main functions of Vitamin D3 includes regulation of calcium, magnesium and phosphorus circulation. Vitamin D3 helps to retain these substances in bones, combats atherosclerosis, and regulates assimilation of calcium and phosphorus in intestines. Major amounts of Vitamin D are necessary in pregnancy or in cases of kidney and liver disorders. Vitamin D deficiency results in softening of bones, disorders of teeth growth. Science researches that prove the effectiveness Calcium researches *Those people (older than 65 years), who have used calcium and vitamin D for 3 years, had bone mass declining slowlier and the number of breaks decreased in 7 % (Dawson-Hughes). * After accomplishing multicentral researches it was identified that the usage of calcium can help pregnant women to avoid the increase of arterial blood pressure that is evoked by the pregnancy (Levine RJ, Hauth JC, Curet LB, et al. Trial of calcium to prevent preeclampsia. N Engl J Med. 1997;337(2):69-76.). * After accomplishing placebo auditorial researches it was identified that the usage of calcium helps elder woman to reduce weight (Davies KM, Heaney RP, Recker RR, Lappe JM, Barger-Lux MJ, Rafferty K, Hinders S. Calcium intake and body weight. J Clin Endocrinol Metabol. 2000;85(12):4635-4638.). *Calcium can help in order to avoid hypertension, thus it can also be used additionally while healing hypertension (Miller GD, DiRienzo DD, Reusser ME, McCarron DA. Benefits of dairy product consumption on blood pressure in humans: a summary of the biomedical literature. J Am Coll Nutr. 2000;19(2 Suppl):147S-164S). Magnesium researches *60 patients were distinguished into 2 groups. One group used magnesium, another – placebo. For 12 hours was monitored arterial blood pressure, pulse, amount of magnesium in the serum. Conclusion: magnesium was positively tolerated; there were no side effects, dangerous decrease of blood pressure or thinning of the pulse (Muir KW, Lees KR.,University Department of Medicine and Therapeutics, Gardiner Institute, Western Infirmary, Glasgow, Scotland.). *After accomplishing multicentral researches it was proven that magnesium has a neuroprotective effect, improves blood circulation (Muir KW, Department of Neurology, Southern General Hospital, Glasgow, Scotland.). *Magnesium significantly reduces the frequency of various heartbeat disorders (American Journal of Clinical Nutrition 2002; 75:550-554; Klevay LM, Milne DB, Am J Clin Nutr. 2002;75:550-554.). *During latter 20 years there were accomplished 16 researches and was determined that magnesium is useful while healing hypertension (Hypertension 31 (Part 1): 131, 1998.). *Those, which have used 350 mg of magnesium per day for one year, had less various heart work strokes and sudden deaths, caused by heart diseases (British Medical Journal 307: 585, 1993.). *40 patients, who had migraine, have used 600 mg of magnesium per day for three months, after what there was determined, that the number of migraine strokes had decreased (Cephalalgia 16: 257, 1996.). Dosage Literature 1. Moorkens G, Manuel y Keenoy B, Vertommen J, et al. Magnesium deficit in a sample of the Belgian population presenting with chronic fatigue. Magnes Res 1997;10:329–37.
2. Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet 1991;337:757–60. 3. Howard JM, Davies S, Hunnisett A. Magnesium and chronic fatigue syndrome. Lancet 1992;340:426. 4.Shils ME. Modern Nutrition in Health and Disease. 9th ed. Baltimore: Williams & Wilkins, 1999. 5. Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. Washington DC: The National Academies Press, 1997. 6. Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. National Academy Press, Washington, DC, 1999. 7. DeLuca HF and Zierold C. Mechanisms and functions of vitamin D. Nutr Rev 1998;56:S4-10. [PubMed abstract] 8. Reichel H, Koeffler H, Norman AW. The role of vitamin D endocrine system in health and disease. N Engl J Med 1989;320:980-91. [PubMed abstract] 9. van den Berg H. Bioavailability of vitamin D. Eur J Clin Nutr 1997;51 Suppl 1:S76-9. [PubMed abstract] 10. Sandstead HH. Understanding zinc: Recent observations and interpretations. J Lab Clin Med 1994;124:322-327. 11. Fabris N and Mocchegiani E. Zinc, human diseases and aging. Aging (Milano) 1995;7:77-93. 12. Hambidge KM, Mild zinc deficiency in human subjects. In: Mills CF, ed. Zinc in Human Biology, New York: Springer-Verlag 1989 Pp 281-296. 13. Horrobin K. Calcium metabolism, osteoporosis and essential fatty acids: a review. Progress in Lipid Research, 1997;36(2- 3):131-151. |
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