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Nutritional supplement Composition
One capsule contains: - Vitamin B1 - 15 mg,
- Vitamin B2 - 15 mg,
- Vitamin B6 - 15 mg,
- Vitamin B12 - 25 mcg,
- Calcium panthotenate - 25 mg,
- Nicotinamide - 50 mg,
- Biotin - 200 mcg.
Recommendations for use: - for better functioning of the nervous system and blood formation.
Effect of active substances
Vitamins are organic compounds of low organic weight. They are essential to body development, growth and activity. Vitamins catalyze metabolism and participate in biochemical reactions of tissues and organs. B-group Vitamins B-group Vitamins are water soluble and well assimilated if administered per os. B1 participates in carbohydrate metabolism, influences neural impulse to the muscles, stimulates normal growth, and reduces acidosis. Vitamin B2 has effect on fat assimilation. It is also important for sight in addition to its ability to stimulate formation of erythrocytes and antibodies. B2 is beneficial for healthy skin, mucous membranes, hair and adrenal function. Vitamin B6 influences fermentation especially in the brain, stimulates hemoglobin production, fat and carbohydrate metabolism. Vitamin B12 participates in important metabolic processes, controls accumulation of energy in muscle tissues as well as blood formation processes. Vitamin B12 participates in cell division by transferring genetic information to new cells. Nicotinamide assists oxidation-reduction reactions and is essential to hormone synthesis and release of bile and gastric juice. Biotin participates in metabolic processes, synthesis of fatty acids and gluconeogenesis. As a coferment, Calcium Pantotenate participates in protein, fat and carbohydrate metabolism, has a lypotrophic and detoxifying action.. Initial symptoms of vitamin deficiency: general asthenia, fatigue, anorexia, reduced immunity. Manifestation of deficiency in specific vitamins becomes evident later. Vitamin B1 deficiency symptoms: inflammatory peripheral nerves disorders, cardiomiopathy, heart disorders, digestive disorders, thyroid gland and hypophysis disorders. Vitamin B2 deficiency symptoms: cheilosis- disorders of the mucous gland, especially mouth. It’s symptoms include painful and light-sensitive eyes, painful cracks at the corners of the mouth, Glossitis, skin inflammation. Vitamin B6 deficiency symptoms: seborrhea dermatitis, anemia, fat infiltration into liver, epileptiformic attacks, ataxia. Vitamin B12 deficiency symptoms: anemia, burning pains in mouth cavity, atrophy of tongue papillae, taste disturbances, smooth and red tongue, nausea. Nikotinamide deficiency symptoms: memory and thought disorders, pelagria, changes in skin and functions of nervous system and digestive tract, spasms of peripheral blood vessels . Biotin deficiency symptoms: muscle pains, dry skin of hand and legs, depression. Calcium Pantotenate deficiency symptoms: hair loss and split, skin inflammations. B-group vitamins are essential for normal metabolic processes of the body. Intake of Vitamin B combination in higher doses results in stronger analgesic effect and therefore is useful in various inflammatory pains.
Dosage 1 capsule once or twice a day with or after meals.
Literatūra:
1. Bhat KS. Nutritional status of thiamine, riboflavin and pyridoxine in cataract patients. Nutr Rep Int 1987;36:685–92. 2. Prchal JT, Conrad ME, Skalka HW. Association of presenile cataracts with heterozygosity for galactosaemic states and with riboflavin deficiency. Lancet 1978;1:12–3. 3. Heap LC, Peters TJ, Wessely S. Vitamin B status in patients with chronic fatigue syndrome. J R Soc Med 1999;92:183–5. 4. Grant JE, Veldee MS, Buchwald D. Analysis of dietary intake and selected nutrient concentrations in patients with chronic fatigue syndrome. J Am Diet Assoc 1996;96:383–6. 5. Snow CF. Laboratory diagnosis of vitamin B12 and folate deficiency. A guide for the primary care physician. Arch Intern Med 1999;159:1289–98 [review]. 6. Rana S, D’Amico F, Merenstein JH. Relationship of vitamin B12 deficiency with incontinence in older people. J Am Geriatr Soc 1998;46:931 [letter]. 7. Houston DK, Johnson MA, Nozza RJ, et al. Age-related hearing loss, vitamin B-12, and folate in elderly women. Am J Clin Nutr 1999;69:564–71. 8. Bostom AG, Silbershatz H, Rosenberg IH, et al. Non-fasting plasma total homocysteine levels and all-cause and cardiovascular disease mortality in elderly Framingham men and women. Arch Intern Med 1999;159:1077–80. 9. Ubbink JB, Vermaak WJH, van der Merwe A, Becker PJ. Vitamin B12, vitamin B6, and folate nutritional status in men with hyperhomocysteinemia. Am J Clin Nutr 1993;57:47–53. 10. Dierkes J, Kroesen M, Pietrzik K. Folic acid and vitamin B6 supplementation and plasma homocysteine concentrations in healthy young women. Int J Vitam Nutr Res 1998;68:98–103. 11. Farmakologija 1986 m., 316–320 psl.
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